hrp0092p3-65 | Diabetes and Insulin | ESPE2019

Insulin-Induced Oedema in a Child with Newly Diagnosed Diabetes Mellitus

Cakir Meltem Didem , Baysal Ozlem

Oedema is a care complication of insulin therapy. It affects mainly patients with newly diagnosed type 1 diabetes mellitus, poorly controlled diabetes mellitus or patients on large doses of insulin. There are only a few case report showing that it is an uncommon and probably an under-reported complication. Two mecanisms are known: the sodium and water retention and vasoactive mediators release. The oedema tends to develop shortly after initiation of insulin therapy and resolve...

hrp0086p2-p875 | Syndromes: Mechanisms and Management P2 | ESPE2016

Tricho-Rhino-Phalangeal Syndrome Type I in a Girl with Growth Hormone Deficiency

Cakir Meltem Didem , Altintas Zuhal , Bozdogan Sevcan Tug

Tricho-rhino-phalangeal syndrome Type I (TRPS I) is a rare autosomal dominant genetic disorder clinically characterized by craniofacial and skeletal abnormalities, associated with cone-shaped epiphyses, brachydactyly and short stature. Although patients with TRPS I present various degrees of short stature, there are only four reports of growth hormone deficiency in patients with TRPS I. We present the case of TRPS I and partial GH deficiency. A 15-year-old female was referred ...